{"id":3854,"date":"2021-08-12T11:16:29","date_gmt":"2021-08-12T15:16:29","guid":{"rendered":"http:\/\/montclare.poly.edu\/?p=3854"},"modified":"2021-08-18T12:53:50","modified_gmt":"2021-08-18T16:53:50","slug":"a-not-so-typical-year-of-an-undergraduate-student","status":"publish","type":"post","link":"http:\/\/montclare.poly.edu\/?p=3854","title":{"rendered":"A (Not so Typical) Year of an Undergraduate Student"},"content":{"rendered":"<p>By: Bonnie Lin<\/p>\n<p>&nbsp;<\/p>\n<p>March 11 th , 2020: NYU announced that all classes and non-essential research will be conducted<br \/>\nremotely as a precautionary measure for the COVID-19 issue that is getting worse. The sudden<br \/>\ntransition into remote instruction was and still is, met with several challenges. However, classes<br \/>\nstill managed to move forward with a combination of Zoom and online exams.<br \/>\nResearch on the other hand is even more difficult, or even impossible, to fully transition to<br \/>\nremote operation. Ongoing efforts of research through remote settings increased to avoid<br \/>\ndelay in research. Despite increased focus on literature research and computational<br \/>\nsimulations, findings ultimately required experimental confirmation traditionally conducted<br \/>\nthrough wet bench research in a laboratory setting.<\/p>\n<p>June 1 st , 2020: Remote research in computational design starts. As a Thompson Bartlett Fellow,<br \/>\nI worked on computationally designing phosphotriesterase (PTE) variants through incorporation<br \/>\nof non-canonical amino acid, p-fluorophenylalanine, to detoxify organophosphates. For ten<br \/>\nweeks, I was able to familiarize with the computational modeling software, Rosetta, and was<br \/>\nable to identify PTE candidates with increased catalytic efficiency and binding affinity with the<br \/>\nhelp of my mentor Farbod Mahmoudinobar and Dr. Montclare.<\/p>\n<p>The idea of approaching protein engineering from a different perspective was full of challenge<br \/>\nand excitement. Both computational design through remote operation and wet bench research<br \/>\nare similar in two ways: that lasting feeling of accomplishment to participate and contribute to<br \/>\nthe world of scientific discoveries and findings.<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/montclare.poly.edu\/wp-content\/uploads\/2021\/08\/Covid.jpg\"><img loading=\"lazy\" decoding=\"async\" alt=\"Covid\" src=\"http:\/\/montclare.poly.edu\/wp-content\/uploads\/2021\/08\/Covid.jpg\" width=\"311\" height=\"162\" \/><\/a><\/p>\n<p><a href=\"http:\/\/montclare.poly.edu\/wp-content\/uploads\/2021\/08\/Covid.jpg\">https:\/\/www.ehstoday.com\/covid19\/article\/21150185\/cdc-cuts-covid19-quarantine-time-for-exposure-to-others<\/a><\/p>\n<p>Fall 2020: Classes are being held through a wide range of flexibility to accommodate students in<br \/>\nthe midst of a pandemic. Undergraduates are offered a choice of taking in-person classes, fully<br \/>\nremote or blended (hybrid version). Laboratory courses are offered in-person only and for<br \/>\nthose that cannot attend in-person have the option of taking these courses the following<br \/>\nsemester. Research can now be conducted in-person but under certain restrictions and safety<br \/>\nprecautions.<\/p>\n<p>Although I enjoyed research from a different approach (computational design), I was ready and<br \/>\neager to go back on campus. I was always a hands-on type of learner. I missed pipetting. I<br \/>\nmissed protein expression and purification and struggling with making a dialysis bag. I missed<br \/>\nperforming protein characterization studies. I missed being able to conduct an experiment with<br \/>\nmy own hands and seeing results with my own eyes. However, what I missed the most is that<br \/>\nfeeling, that feeling of anticipation while waiting for your analysis results, that feeling of<br \/>\nexcitement to see results that agree with your previous studies, that feeling of observing<br \/>\nsomething different that might open the doors to unexpected discoveries fueled by our very<br \/>\nown curiosity. Despite the restrictions and precautions that needed to be taken, I was very<br \/>\neager to go back to lab.<\/p>\n<p>September 2 nd , 2020- My alarm rang earlier than usual as now I need to take commute into<br \/>\naccount. After getting ready and completing the daily screener, I headed off to Tandon at<br \/>\n7:30AM. Due to safety concerns, instead of taking the subway (my usual form of commute<br \/>\nbefore the pandemic), I decided to drive to school which usually takes 1 hour with the traffic in<br \/>\nthe morning. At around 8:30AM, I arrived at Tandon, tapped my ID and showed my completed<br \/>\ndaily screener to the security officer.<\/p>\n<p>11:00AM: After attending my first class, I made my way up to my research lab on the 8 th floor.<br \/>\nAlthough some remained the same, many changes have been made: 6 feet social distancing<br \/>\nwhere each research personnel are located at every other bench, laboratory shifts being<br \/>\nimplemented to avoid everyone coming in all at once, limited capacity in the office space,<br \/>\ncontact tracing and etc. Despite the changes being made, as soon as I held my first pipette of<br \/>\nthe day to conduct my experiment, that feeling soon surged back into me. With added safety<br \/>\nprecaution, I submerged myself into that feeling I missed for six months and got right to work.<\/p>\n<p>Even with the midst of the pandemic, research is still ongoing. Even with the added boundaries<br \/>\ncreated by the pandemic, scientific discoveries are still being made every second every minute<br \/>\nevery day. Why? Because science has no boundaries.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>By: Bonnie Lin &nbsp; March 11 th , 2020: NYU announced that all classes and non-essential research will be conducted remotely as a precautionary measure for the COVID-19 issue that is getting worse. The sudden transition into remote instruction was and still is, met with several challenges. However, classes still managed to move forward with&hellip; <a class=\"more-link\" href=\"http:\/\/montclare.poly.edu\/?p=3854\">Continue reading <span class=\"screen-reader-text\">A (Not so Typical) Year of an Undergraduate Student<\/span><\/a><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[38],"tags":[],"class_list":["post-3854","post","type-post","status-publish","format-standard","hentry","category-blog-posts","entry"],"_links":{"self":[{"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=\/wp\/v2\/posts\/3854","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3854"}],"version-history":[{"count":4,"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=\/wp\/v2\/posts\/3854\/revisions"}],"predecessor-version":[{"id":3860,"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=\/wp\/v2\/posts\/3854\/revisions\/3860"}],"wp:attachment":[{"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3854"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3854"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/montclare.poly.edu\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3854"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}